Cytoreductive Surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a specialized line of treatment for cancer patients who are diagnosed with tumors or peritoneal surface malignancies. CRS + HIPEC is significantly effective for almost disease free survival in most patients.
With extensive research in the field of Cancer, a new methodology has evolved in the therapeutic approach that combines surgery and radiation therapy not only to remove the tumor but to also contain its further spread.
PSM or peritoneal surface malignancy is an advanced stage of cancer in the tumor that gives the patient a very short time to live if untreated. Earlier only palliative care was given to the patient to make his/her end as comfortable as humanly possible. With the advance in research and cancer treatment, CRS + HIPEC not only gives a new lease of life to the patient, but an almost disease free survival.
Dr Krunal Khobragade procedure for CRS+ HIPEC for prolonged disease free survival:
- Pre-operative patient evaluation with CT, PET, MRI scans
- Coordination with other specialities
- The actual surgery process:
- Median Laparotomy ie opening of the abdomen to see the abdominal cavity
- Visible cancerous tumors are removed surgically from the abdominal cavity
- To kill remainder of cancer cell, the cavity is bathed with hot chemotherapy
- The extreme hot temperature (augments the effect of chemotherapy on the cytotoxic cells
- The intraperitoneal tubes effectively deliver higher doses to the localized regions
- This minimizes the toxic effect of chemotherapy on the body
Peritoneal sarcoma is a rare form of cancer that must be diagnosed early and in most patients can be effectively treated by CRS + HIPEC. The surgery lasts for about 7 hours and the stay at hospital post surgery is usually around 12 days.