Cytoreductive Surgery & HIPEC in Nagpur | Peritoneal Cancer Treatment | Dr. Krunal Khobragade

Cytoreductive Surgery & HIPEC in Nagpur | Peritoneal Cancer Treatment | Dr. Krunal Khobragade
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Cytoreductive Surgery & HIPEC in Nagpur

HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is a specialised, team-based treatment approach for selected patients with peritoneal cancers (cancer spread within the abdominal lining). This page explains eligibility, the procedure, recovery, and common patient questions—so you can make informed decisions.

Important: HIPEC is not suitable for every patient. Final suitability is decided after clinical evaluation, imaging, and a detailed discussion of risks, benefits, and alternatives.
Peritoneal Cancer Cytoreductive Surgery Heated Chemotherapy Ovarian • Colorectal • Appendix Nagpur Consultation

What Is Cytoreductive Surgery with HIPEC?

Cytoreductive Surgery with HIPEC is an advanced treatment approach used for selected patients with cancer affecting the peritoneum (the lining of the abdominal cavity). It typically includes:

  • Cytoreductive Surgery (CRS): removing visible tumour deposits from the abdomen where feasible.
  • HIPEC: circulating warmed chemotherapy (usually ~41–43°C) inside the abdomen for a set time to target microscopic disease.

Why HIPEC is Different

HIPEC delivers chemotherapy directly where disease is present, and heat may help chemotherapy penetration. The aim is to treat microscopic disease after maximal surgical removal of visible disease—within a carefully selected group of patients.

Medical information notice: Content is for education and does not replace medical advice. Treatment decisions are individualised.

Who May Be Eligible for HIPEC?

HIPEC is usually considered after evaluation of:

  • Type and origin of cancer
  • Extent of peritoneal involvement (disease burden)
  • Whether complete/near-complete cytoreduction appears feasible
  • Overall fitness for major surgery (heart/lung/kidney function, nutrition, performance status)
  • Prior treatments and response

Conditions Where HIPEC May Be Discussed

  • Ovarian cancer with peritoneal spread (selected cases)
  • Colorectal cancer with peritoneal metastasis (selected cases)
  • Appendiceal cancers / pseudomyxoma peritonei (where applicable)
  • Selected cases of other GI cancers with limited peritoneal involvement (as clinically appropriate)
A consultation typically includes history, examination, review of imaging (CT/PET-CT), pathology, tumour markers, and treatment history.

How HIPEC Surgery Is Performed

HIPEC is performed in an operating theatre by a specialised multidisciplinary team. The exact technique can vary by cancer type and institutional protocol.

Step 1: Cytoreductive Surgery (CRS) Removal of visible tumour deposits from the peritoneal surfaces and involved areas where feasible.
Step 2: HIPEC (Heated Intraperitoneal Chemotherapy) Heated chemotherapy is circulated inside the abdomen for a defined duration to treat microscopic disease.
Step 3: Completion & Post-Operative Care After HIPEC, the perfusate is drained, surgery is completed, and recovery begins in a monitored setting.

Before Your HIPEC Consultation (Checklist)

  • Latest imaging (CT / PET-CT), biopsy report, histopathology
  • Chemo / radiotherapy details (cycles, drugs, dates)
  • Discharge summaries / prior operative notes (if any)
  • Blood reports (CBC, kidney/liver function, tumour markers if advised)

Recovery After Cytoreductive Surgery & HIPEC

Recovery depends on disease extent, surgery complexity, and the patient’s baseline health. Many patients require careful monitoring for nutrition, bowel function, and wound healing.

Typical Recovery Milestones

  • Hospital stay: commonly around 7–14 days (varies by case)
  • Early recovery: gradual activity increase over 4–6 weeks
  • Follow-ups: planned visits for wound review, diet guidance, and ongoing cancer care planning
Your team will provide personalised instructions on diet, movement, medications, and warning signs to watch for after discharge.

Risks, Safety & What to Expect

Cytoreductive surgery with HIPEC is a major procedure. Like all complex surgeries, it can have risks. These are discussed in detail during consultation and consent.

Possible Risks (Case-Dependent)

  • Bleeding, infection, fluid imbalance
  • Temporary bowel slowing / ileus
  • Leak risk where bowel surgery is involved (if applicable)
  • Fatigue and longer recovery due to procedure intensity

A key part of HIPEC planning is selecting patients where the expected benefit outweighs the risks. Your surgeon will explain suitability and alternatives based on your clinical scenario.

Why Consult Dr. Krunal Khobragade for HIPEC in Nagpur?

Dr. Krunal Khobragade focuses on advanced surgical oncology approaches for GI and peritoneal cancers, including cytoreductive surgery and HIPEC. A consultation includes:

  • Eligibility assessment (reports + imaging review)
  • Clear explanation of procedure, recovery, and realistic expectations
  • Multidisciplinary planning with personalised treatment sequencing
  • Second opinion support if you already have a diagnosis and plan
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HIPEC FAQs

HIPEC is heated chemotherapy given inside the abdomen during surgery, after removing visible cancer deposits. It is used for selected peritoneal cancers where this approach is appropriate.
HIPEC may be discussed for selected peritoneal cancers—commonly those related to ovarian, colorectal, and appendiceal origins. Suitability depends on disease extent, health status, and expected ability to remove visible disease.
HIPEC is a complex procedure and carries risks like any major surgery. Safety depends on careful patient selection, experienced surgical care, and close post-operative monitoring.
Many patients need around 7–14 days in hospital (varies by case) and several weeks for gradual recovery. Your surgeon will give a personalised recovery plan based on your procedure details and overall health.
Not always. HIPEC can be part of a broader treatment plan. Some patients also need systemic therapy depending on cancer type, stage, and tumour biology.
Eligibility is decided after reviewing imaging (CT/PET-CT), biopsy/histopathology, prior treatment history, and your overall fitness for major surgery. Book a consultation with reports for a clear recommendation.

Book a Consultation for HIPEC in Nagpur

If you have been told the cancer has spread within the abdomen (peritoneal disease), or you are seeking a second opinion for advanced treatment options, you can consult Dr. Krunal Khobragade for an evaluation.

No-claims policy: Outcomes vary between patients. Treatment decisions are individualised after clinical evaluation.
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